“Unnecessary Drugs” as well as F758 “Psychotropic medications/prn use,” both implemented in Phase 2 of the Mega-rule, will have a significant impact on medication use in LTCFs. Together, these F-Tags define and address the concept of “Unnecessary Drugs” and continue the requirement for gradual dosage reduction (GDR) of psychotropic medications that was stipulated in the former F329. However, the term “psychotropic medications” now includes antipsychotics, antidepressants, anti-anxiety agents and hypnotics as well as, ”any drug that affects brain activities associated with the mental process and behavior.”